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Acinic cell carcinoma is a malignant tumor representing 2% of all salivary tumors. 90% of the time found in the parotid gland, 10% intraorally on buccal mucosa or palate. The disease presents as a slow growing mass, associated with pain or tenderness in 50% of the cases. Often appears pseudoencapsulated. == Histology == Basophilic, bland cells similar to acinar cells. Growth pattern: solid - acinar cells, microsytic - small systic spaces mucinous or eosinophilic, papillary-custic - large cystic lined by epithelium, follicular - similar to thyroid tissue. These tumors which resemble serous acinar cells vary in their behavior from locally aggressive to blatantly malignant. It can also appear in the breast. The pancreatic form of acinic cell carcinoma is a rare subtype of exocrine pancreatic cancer. Exocrine pancreatic cancers are the most common form of pancreatic cancer when compared to endocrine pancreatic cancer. Acinic cell carcinomas arise most frequently in the parotid gland. Other sites of primary tumors have included the submandibular gland and other major and minor salivary glands. There have been rare cases of primary tumors involving the parapharyngeal space and the sublingual gland. 〔 "Acinic Cell Carcinoma Overview." Acinic Cell Carcinoma Information Center. Web. 07 Dec. 2009. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Acinic cell carcinoma」の詳細全文を読む スポンサード リンク
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